Member Publications
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104 Member Publications for June
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Pathways of copper import and utilization that support respiration in Bacillus subtilis.
- mBio - published June 9, 2026
- Barnes G, Hederstedt L, Fisher OS, von Wachenfeldt C, Helmann JD
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Oxidative Characteristics of Turkey Hemoglobin A Containing Covalently Bound Epigallocatechin Gallate.
- J Agric Food Chem - published June 9, 2026
- Yin J, Zhang W, Tatiyaborworntham N, Bingman CA, Richards MP
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ClpX-dependent regulatory pathway exacerbates Streptococcus pyogenes pathogenesis in diabetic skin infection.
- mBio - published June 9, 2026
- Liu S, Rosen AL, Olson BS, Lu Y, Hickerson S, Kau AL, Hultgren SJ, Caparon MG, Xu W
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Service Year-Dependent Disruption of Reproductive Hormones and Altered DNA Methylation in Male Firefighters.
- J Occup Environ Med - published June 9, 2026
- Leung YK, Ouyang B, Cheong A, Karyala SV, Chen J, Medvedovic M, Ying J, Ho SM
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Biochemical basis for LRP1 interaction with Rift Valley fever virus glycoprotein and its role in viral entry.
- J Mol Biol - published June 9, 2026
- Fatma F, Price DA, Rush RE, Allen C, Stuckmeyer H, Brown G, Brett TJ, Hartman AL, Leung DW, Amarasinghe GK
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LRP4 is an entry receptor for multiple encephalitic alphaviruses.
- Nat Commun - published June 9, 2026
- Tian S, Ma B, Guo H, Chong Z, Gilliland TC Jr, Hui S, Wang G, Zhang Y, Zhou J, Sariol A, Sun X, Hu Y, He Z, Fremont DH, Klimstra WB, Diamond MS, Xiang Y, Zhang R
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EsxA is required for antibacterial toxin export by the type VIIb secretion system.
- J Biol Chem - published June 9, 2026
- Shah PY, Garrett SR, Klein TA, Pfoh R, Raphenya AR, McArthur AG, Howell PL, Whitney JC
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Control of the committed step in lipopolysaccharide biosynthesis.
- J Biol Chem - published June 9, 2026
- Mi W, Nathawat R, Wang H, Delgado S
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Endurance exercise elicits temporal and sexual dimorphic multi-omics remodeling of liver metabolism revealed by MoTrPAC.
- Cell Rep - published June 8, 2026
- Kelty TJ, Franczak E, Gay NR, Many GM, Sagendorf TJ, Sanford JA, Hou Z, Gaul DA, Fernández FM, Rekowski M, Burant CF, Hevener AL, Adkins JN, Bodine S, Lindholm ME, Ortlund EA, Schenk S, Thyfault JP, Rector RS, MoTrPAC study group
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KNexPHENIX: A PHENIX-Based Workflow for Improving Cryo-EM and Crystallographic Structural Models.
- J Chem Inf Model - published June 8, 2026
- Nandi S, Conn GL
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Hit-to-Lead Optimization of Energy-Coupling Factor (ECF) Transporter Inhibitors as Novel Antibiotic.
- J Med Chem - published June 6, 2026
- Exapicheidou I, Tsarenko A, Zeller L, Ibrahim H, Baumann C, Shams A, Hoffmann PA, Li Y, Kany AM, Hermann J, Slotboom DJ, Müller R, Volkamer A, Hamed MM, Diamanti E, Hirsch AKH
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Lipid composition and mechanical force underlie multi-modal regulation of Piezo1 gating.
- Sci Adv - published June 5, 2026
- Vaisey G, MacKinnon R
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Century of Progress on the Structure of APOB-100 in Atherogenic Lipoproteins.
- Circ Res - published June 5, 2026
- Coleman B, Woollett LA, Davidson WS
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Evaluating beta-tubulin variants as predictors of benzimidazole resistance across Caenorhabditis nematodes.
- PLoS Pathog - published June 5, 2026
- Shaver AO, McKeown R, Reyes Otero JM, Collins JB, Hogan DW, Fraser JS, Dreyer SM, Ragsdale EJ, Andersen EC
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Cisplatin resistance in an ovarian cancer model is mediated by microtubule dynamics regulator TPPP3 in synergy with tubulin code rewiring.
- Cell Rep - published June 4, 2026
- Horibata S, Mahalingan KK, Patel R, Fan Y, Hotz JM, Ponton-Almodovar A, MacRenaris K, Li Y, Meerzaman D, Gottesman MM, Roll-Mecak A
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Structural dynamics of kappa opioid receptor interactions with β-arrestin 1.
- Nat Commun - published June 4, 2026
- Han J, Fine EJ, Jiang Q, Zhuang Y, Suomivuori CM, Chen ZW, Denn E, Whiddon K, Li K, Evers AS, Fuller J, Carter J, Fay JF, Chen M, Dror RO, Che T
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An S752D activation loop mutation dynamically primes Muscle-Specific Kinase (MuSK) for activation.
- Biochem J - published June 4, 2026
- Prömer JJ, Murphy JW, Lemmon MA, Tsutsui Y, Herbst R
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Prolonged zinc exposure modulates biofilm metabolic activity and conjugation in Enterococcus faecalis.
- BMC Microbiol - published June 4, 2026
- Fenclova D, Hrazdilova K, Coufalova M, Ter Beek J, Berntsson RP, Zurek L, Cihalova K
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A cross-vertebrate brain protein interaction map identifies conserved neural and non-neural complexes.
- Cell Rep - published June 4, 2026
- Dang V, Voigt B, Yang D, Hoogerbrugge G, Lee M, Cox RM, Papoulas O, McWhite CD, Pradeep R, Leggere JC, Neely BA, Gray RS, Marcotte EM
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Implementation of SCALE-UP in First-Year Chemistry at an HBCU.
- J High Educ Theory Pract - published June 4, 2026
- Erebholo F, Chakafana G, Holder C, Hahn IF, Ndip EM, Njoki PN, Whittington D, Asojo OA
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A GUV-based assay to reconstitute membrane tethering in vitro.
- Mol Biol Cell - published June 3, 2026
- Andhare D, Ragusa MJ
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LpxC activity regulation: An emerging paradigm for controlling lipopolysaccharide synthesis.
- Trends Microbiol - published June 3, 2026
- Nathawat R, Liu C, Mi W
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Neutralizing antibodies elicited in nonhuman primates by an enterovirus D68 virus-like particle vaccine target receptor binding sites.
- Sci Transl Med - published June 3, 2026
- Moss DL, Cheng J, Krug PW, Paine AC, Fisher BE, Henry AR, Roberts-Torres J, Johnston TS, Smith SC, Pletnev S, Lei H, Morano NC, Pierson TC, Shapiro L, Zhou T, Kwong PD, Douek DC, Kanekiyo M, Ruckwardt TJ
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Reply to Hojný et al.: Fusion-driven vs. fusion-negative high-grade endometrial stromal sarcoma.
- Proc Natl Acad Sci U S A - published June 3, 2026
- Hartwich TMP, Choi J, Schlessinger J, Santin AD
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Cellular assembly and functional resilience of the mammalian RNA exosome.
- EMBO J - published June 2, 2026
- Navalayeu T, Beer N, Bebjaková M, Kalis RW, Hohmann U, Stejskal K, Krššáková G, Fasching N, Herzog VA, Popitsch N, Roitinger E, Plaschka C, Zuber J, Ameres SL
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Identifying membrane-bound transcriptional regulatory proteins from rare but evolutionarily conserved domain combinations.
- Nucleic Acids Res - published June 2, 2026
- Lee M, Jang Y, Guo Q, Punyamurtula U, Choi J, Kim J, Marcotte EM
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Optimized Digestion Conditions for Membrane Protein Footprinting and Mass Spectrometry Analysis.
- Membranes (Basel) - published June 2, 2026
- Cheng M, Li X, Bai L, Li W, Gross ML
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Arf1 is involved in Neisseria meningitidis-induced cortical branched F-actin network reorganization.
- EMBO Rep - published June 2, 2026
- Sahnine M, Crochet M, Tachon S, Goussard S, Pénard E, Scandola C, Duchateau M, Giai Gianetto Q, Salles A, Moneron G, Swistak L, Charles-Orszag A, Mallet A, Matondo M, Tinevez JY, Bonazzi D, Sartori-Rupp A, Duménil G, Obino D
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Temporal proteomic analysis reveals a three-phase adaptation strategy in Phytophthora cinnamomi during salinity stress.
- J Proteomics - published June 2, 2026
- Vinson LS, Loo T, Kulshreshtha S, Dobson RCJ, Meisrimler CN
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Addressing the zoonotic threat of merbecoviruses.
- Nat Microbiol - published June 2, 2026
- Li X, Kang M, Jiao XY, Merits A, Veit M, Rey FA, Dai H, Wang XY, He WT, Holmes EC, Varjak M, Mahalingam S, Wang D, Jiang Z, Wang S, Li X, Peng Z, He N, Su S
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Tubulin flux at spastin-induced nanodamage sites regulates microtubule rescue frequency and EB1 lifetimes.
- Proc Natl Acad Sci U S A - published June 2, 2026
- Szczesna E, Spector JO, Sarbanes SL, Chen J, Szyk A, Roll-Mecak A
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Functional diversity of phage sponge proteins that sequester host immune signals.
- Nat Microbiol - published June 2, 2026
- Hadary R, Chang RB, Béchon N, Tal N, Osterman I, Yirmiya E, Garb J, Rivera ML, Amitai G, Kranzusch PJ, Sorek R
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Plant cell wall-plasma membrane attachments mediate stress resilience through cellulose synthase complexes and remorins.
- Cell - published June 2, 2026
- Rui Y, Zaoralová M, Dwyer WP, Reyes AV, Grismer TS, Abel NB, Jayachandran D, Chundawat SPS, Ott T, Kieber JJ, Dahlberg PD, Xu SL, Dinneny JR
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Comprehensive mapping of human CD4(+) T cell epitopes for Nipah and measles as prototype Paramyxoviruses.
- Cell Rep Med - published June 2, 2026
- Tarke A, Macias M, Morales CF, Michaelis T, Siddiqui L, Yu ED, Trevizani R, Zuniga A, Zmasek C, Phillips E, Mallal S, Lin B, Estevez JO, Erlich JR, Johnson NV, McLellan JS, Frazier A, da Silva Antunes R, Tan GS, Grifoni A, Sette A
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Structural Response of Pohlianin C to Heterocyclic Graft Incorporation.
- J Org Chem - published June 2, 2026
- Širvinskas MJ, Ou YD, Saunders GJ, Yudin AK
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High-throughput protein target mapping enables accelerated bioactivity discovery for ToxCast and PFAS compounds.
- Proc Natl Acad Sci U S A - published June 2, 2026
- Yang D, Wang X, Liu J, Gong Y, Nair P, Sun J, Qian X, Cui J, Zeng H, Dong A, Harding RJ, Burgess-Brown N, Beyett TS, Song D, Krause HM, Diamond ML, Bolhuis DL, Brown NG, Arrowsmith CH, Edwards AM, Halabelian L, Peng H
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Structural and cellular insights into DCTPP1 antagonists and their synergistic action with DNMT inhibitors.
- Proc Natl Acad Sci U S A - published June 2, 2026
- Hauk G, Liu J, Nelson WG, Yegnasubramanian S, Berger JM
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Structural basis of nonmuscle myosin-2 autoinhibition mechanisms.
- Nat Commun - published June 2, 2026
- Heissler SM, Grandinetti G, Sellers JR, Chinthalapudi K
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A Thymine Dimer Stalls a High-Fidelity DNA Polymerase by Providing No Template Information in the Same Manner as an Abasic Site.
- Biochemistry - published June 2, 2026
- Walsh AR, Kim HR, Beese LS, Wu EY
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Structural basis of opioid receptor activation by PCP and ketamine.
- Nat Struct Mol Biol - published June 2, 2026
- Jiang Q, Han J, Fine EJ, Ramos-Gonzalez N, Rangari VA, Ruiz MV, Critz ML, Suomivuori CM, Wang J, Albert TL, Whiddon K, Li K, Robertson MJ, Huang XP, Land BB, Majumdar S, Fay JF, Dror RO, Che T
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Analysis of West Nile disease convalescents identifies human monoclonal antibodies protective against West Nile and related orthoflaviviruses.
- Immunity - published June 2, 2026
- Cervantes Rincón T, Frckova T, Contejean ZI, Cantergiani J, Groen K, Cena B, Moro SG, Bianchini F, Simonelli L, Jarrossay D, Tosolini S, Kuratli R, Robinson ARE, Cizkova M, Niejadlik EG, Moritz J, Thakur R, Krátka Z, Mijatović D, Grujić J, Holoubek J, Budakov-Obradović Z, Salat J, Hönig V, Vraneš M, Lojpur Z, Lendak D, Sević S, Bajči M, Popović-Dragonjić L, Popovska Jovičić B, Gavrilović J, Kapoor T, MacDonald MR, Bournazos S, Varani L, Palus M, Hale BG, Banović P, Ruzek D, Barnes CO, Robbiani DF
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Structure basis for single-strand nucleic acid targeting by IscB and variants.
- Nucleic Acids Res - published June 2, 2026
- Xu C, Yang Q, Niu X, Ke A
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Structural Transformation of a BRAF Inhibitor into a Selective PKR Inhibitor.
- J Med Chem - published June 2, 2026
- Yin J, Srivastava S, Tang X, Galbraith C, Uchenunu O, Miller J, Liu Y, Crescenzi I, Kiyota T, Kurinov I, Costa-Mattioli M, Laufer R, Aman A, Rottapel R, Ramnauth J, Haakonsen DL, Uehling DE, Sicheri F
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A ratiometric fluorescent reporter of mitochondrial sodium.
- Nat Chem Biol - published June 2, 2026
- Mitra K, Kim S, Oettinger D, Uthishtran S, Zhao Q, Veetil AT, Ramirez JR, Lin H, Arumugam S, Krishnan Y
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Probing the limits of genetic recoding using multi-omics-guided evolution.
- Nat Commun - published June 2, 2026
- Nyerges A, Chiappino-Pepe A, Budnik B, Baas-Thomas M, Rhuby E, Flynn R, Yan S, Ostrov N, Liu M, Wang M, Zheng Q, Hu F, Chen K, Rudolph A, Chen D, Ahn J, Spencer O, Ayalavarapu V, Tarver A, Harmon-Smith M, Hamilton M, Blaby I, Yoshikuni Y, Hajian B, Jin A, Kintses B, Szamel M, Seregi V, Shen Y, Li Z, Church GM
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Functional dissection of Corynebacterium glutamicum Wag31 domains for septal recruitment and polar distribution during the cell cycle.
- mBio - published June 2, 2026
- Petit J, Megrian D, Martinez M, Sogues A, Brunk G, de Sousa-d'Auria C, Ben Assaya M, Thouvenot C, Lesur E, Bourdreux Y, Bayan N, Alzari PM, Wehenkel AM
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Structural basis for selective and potent degradation of IRAK4 by KT-474.
- Nat Commun - published June 2, 2026
- Fei X, Ramanathan A, Daigle CA, Ford M, Campbell V, Zheng X, Sintchak M, Li H, Kamadurai H, Miller R, Kazmirski S, Huang X, Weiss MM, Mainolfi N, Zhu X
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High-throughput machine learning-aided antibody discovery for cell surface antigens.
- Cell Syst - published June 2, 2026
- Kothiwal D, Kollasch AW, Anuganti M, Hollmer N, Ghosh A, Zhang R, Li H, Paul SB, Li R, Zagar Y, Abdollahi M, Anderson Z, Belay F, Salotto M, Ulmer S, Abdelalim YA, Kachare A, Kumar S, Vangala M, Yang C, Chedotal A, Jardine JG, Teixeira AAR, Moshinsky DJ, Zhu H, Zhu S, Springer TA, Marks DS, Meijers R
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Intraflagellar transport protein IFT172 contains a C-terminal ubiquitin-binding U-box-like domain involved in ciliary signaling.
- Elife - published June 2, 2026
- Zacharia NK, Kuhns S, Boegholm N, Christensen A, Wang J, Petriman NA, Lorentzen A, Fialova JL, Menguy L, Saunier S, Christensen ST, Andersen JS, Bhogaraju S, Lorentzen E
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Structural mechanism of Necrocide 1 activation of human TRPM4 that triggers necrosis by sodium overload.
- Nat Commun - published June 2, 2026
- Teixeira-Duarte CM, Fu W, Zeng W, Wang J, Jiang X, Zhao Z, Zhong Q, Jiang Y
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Bottlebrush polymer conjugates for enhanced antisense oligonucleotide therapy in myotonic dystrophy type 1.
- Nucleic Acids Res - published June 2, 2026
- Li Y, Oetheimer C, Wang Y, Heo GS, Wu J, Chang R, Zhang W, Schneider E, Chen J, Fang Y, Wei Y, Nian K, Zhang H, Sherman L, Liu Y, Zhang K
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Insights into retinal disease and non-tubulin glutamylation from a RPGR-TTLL5 complex structure.
- J Cell Biol - published June 1, 2026
- Park JH, Liu RJY, Sun X, Mahalingan KK, Hiriyanna S, Li T, Roll-Mecak A
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Antibody-mediated diversification of primary and secondary humoral immune responses.
- J Exp Med - published June 1, 2026
- Schaefer-Babajew D, Binet L, Silva Santos GS, Ruprecht C, Deimel LP, ElTanbouly MA, Gharrassi D, Lima Dos Reis G, Uhe C, Yao KH, Hernandez B, Agrawal P, Gazumyan A, Stamatatos L, Hartweger H, Nussenzweig MC
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PIP4K2A/2B inhibitor suppresses tumor growth in a xenograft model of NSCLC.
- iScience - published June 1, 2026
- He Z, Chen S, Bosenberg M, Muthusamy V, Xi Y, Wang H, Micheli F, Cianciulli A, Beato C, Van Zandt M, Ellman J, Ha Y
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Structural basis for high-affinity inhibitor binding to lipid kinases PIP4K2A and PIP4K2B.
- Acta Crystallogr D Struct Biol - published June 1, 2026
- He Z, Chen S, Micheli F, Cianciulli A, Beato C, Ellman J, Ha Y
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Cellular and molecular representations: Following the lesson of David Goodsell.
- Protein Sci - published June 1, 2026
- Zoppè M, Williams VCJ, Briegel A
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Structural basis for dimerization, catalytic regulation, and substrate selectivity of the chloroplast S9D CGEP protease in Arabidopsis thaliana.
- Protein Sci - published June 1, 2026
- Ehrlich JJ, Routray P, Enns L, van Wijk KJ, Kawate T
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Analysis of the heterogenous structural states of the hexameric ATPase PilU of the type IV pili from Vibrio cholerae.
- Protein Sci - published June 1, 2026
- Guo Y, Shukla S, Minasov G, Inniss NL, Klose T, Tokars VL, Mondragón A, Otwinowski Z, Borek D, Satchell KJF
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Targeting BRD2 and BRD4 inhibit the growth of KSHV-infected immortalized endothelial cells through suppression of LANA translation.
- PLoS Pathog - published June 1, 2026
- Chen J, Fan J, Qin M, Lin Z, Mu S, Dai L, Qin Z
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Structure of the E3 ligase CRL2(ZYG11B) with substrates reveals the molecular basis for N-degron recognition and ubiquitination.
- Cell Rep - published June 1, 2026
- Liu X, Li Y, Castro LK, Yu Z, Cheng Y, Daugherty MD, Gross JD
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Generation of membrane-permeable cyclic peptides inhibiting protein-protein interaction.
- Nat Chem Biol - published June 1, 2026
- Ji X, Farrera-Soler L, Li J, Sangouard G, De Sadeleer N, Nielsen AL, Mothukuri GK, Zarda A, Will EJ, Pojer F, Lau K, Heinis C
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Design, synthesis and evaluation of an uncharged broad spectrum quinoline-oxime hybrid for the reactivation of nerve agent-inhibited human acetylcholinesterase.
- Eur J Med Chem - published June 1, 2026
- De Sousa J, Calas AG, De La Mora E, Landry C, Hanak AS, Maryan-Instone A, Gastellier AJ, Coisne C, Courageux C, Hachani J, Gosselet F, Dehouck MP, Rousseau C, Timperley CM, Weik M, Nachon F, Brown RCD, Baati R, Dias J
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Loss of Payload Sensitivity and Other Mechanisms of Resistance to T-DXd in HER2-Mutant NSCLC: Implications for Subsequent Responsiveness to HER2 TKIs.
- J Thorac Oncol - published June 1, 2026
- Nilsson MB, Le X, Poteete A, Yu X, He J, Huang Q, Shibata Y, Liu X, Moran C, Alizadeh AA, Diehn M, Wakelee H, Almanza D, Soltys S, Sugio T, Mutter J, Kang X, Wang R, Jun S, Esfahani MS, Tran H, Xi Y, Hong L, Huo X, Kumar A, Ren X, Oguchi K, Minamiguchi K, Weipert CM, Wang J, Kittler R, Heymach JV
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mRNA delivery of a class 1/4 SARS-CoV-2 neutralizing antibody protects against diverse sarbecoviruses in a lethal mouse challenge model.
- Proc Natl Acad Sci U S A - published June 1, 2026
- Skelly AN, Fan C, Keeffe JR, Ökten AB, Gavor E, Newby ML, Allen JD, Kreider EF, Ding W, Osbaldeston RA, Park Y, Connell AJ, Lituchy MG, Bibollet-Ruche F, Radford KM, P West A Jr, Peña-Hernández MA, Cruickshank K, Liu W, Li Y, Albertus A, McWilliams B, Russell RM, Konrath KM, Torres JL, Yuan M, Gao H, Montefiori DC, Saag MS, Goepfert PA, Kulp DW, Ward AB, Wilson IA, Shaw GM, Andrabi R, Crispin M, Weissman D, Wilen CB, Bjorkman PJ, Hahn BH
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Cryo-EM reveals a right-handed double-helix dimer architecture of PCDH15.
- Proc Natl Acad Sci U S A - published June 1, 2026
- Liang X, Pathak R, Qiu X, Dillard L, Twomey EC, Müller U
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Contributions of conserved and species-specific CagX (VirB9) domains to the assembly and function of the Helicobacter pylori Cag type IV secretion system.
- Infect Immun - published June 1, 2026
- Okoye CD, Frick-Cheng AE, Salmen W, Tran SC, McDonald WH, Loh JT, McClain MS, Lacy DB, Ohi MD, Cover TL
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Semirandom DNA adducts regulate a filamentous defense-associated reverse transcriptase.
- Nat Struct Mol Biol - published June 1, 2026
- Neville N, Johnson NV, Escobar EE, Chiang CH, Nreca A, Johnson SR, Dai N, Hanneman A, Corrêa IR Jr, McLellan JS, Trachman RJ 3rd
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A cocktail of human mAbs targeting the henipavirus fusion and receptor binding proteins provides cross-species neutralization.
- Sci Transl Med - published June 1, 2026
- Guzmán-Solís AA, Ouizougun-Oubari M, Escaffre O, Larsen BB, Lopez M, Locklear S, Kumar M, Juelich TL, Smith JK, Zhang L, Haas GD, Roenicke R, Brambilla L, Oguntuyo KY, Patel AR, Sapse IA, Bowden TA, Tortorella D, Bloom JD, Freiberg AN, Bajic G, Duty JA, Lee B
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Molecular regulation and physiological role of GOLPH3-mediated Golgi retention.
- Nat Commun - published June 1, 2026
- Theodoropoulou A, Nasrallah A, Abriata LA, Abrami L, Da Graça J, Kaysudu I, Talotta F, Marcaida MJ, Anwar MU, Kováč O, Vakhrushev SY, Alonso-Calleja A, Ho S, Asaro A, Mesquita FS, Alieh L, Gehin C, Bracq L, Goršek N, Vacle S, Samurkas A, Prunotto A, Fusar Bassini L, Machala M, Naveiras O, Schjoldager KT, van der Goot FG, Dal Peraro M, D'Angelo G
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SARS-CoV-2 variant booster vaccination and infection alter the breadth of the memory B cell repertoire.
- Sci Transl Med - published June 1, 2026
- Malek R, Matassoli F, Gordon K, Shimberg GD, Mantus GE, Spangler A, Chopde AJ, Teng IT, Zhou T, Lin BC, Carroll R, Kazmierski R, Wang L, Posavad CM, Rouphael NG, Branche AR, Roberts PC, Serebryannyy L, Andrews SF
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Isolation of genome-predicted Caldatribacterium (Atribacterota) reveals pervasive microbial cultivation problem due to folate precipitation.
- Nat Commun - published June 1, 2026
- Hedlund BP, Alvarado T, Sushenko NS, Murphy TR, Torres A, Blocker AM, Lai D, Mayali X, Seymour CO, Muok A, Xiao R, Levon E, Phoenix JT, Mazdra K, Sons T, Doss RK, Vamvakas A, Camacho A, Ledesma J, Jiries J, Manriquez A, Martinez AR, Owerkowicz Z, Lacy J, Weber PK, Briegel A, Moser DP, Pett-Ridge J, Dodsworth JA, Hamilton-Brehm SD
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DNA repair drives cisplatin-induced neuronal death.
- Cell - published June 1, 2026
- Nathan WJ, Chen C, Sakr R, Siqueira Mietto B, van Batenburg V, van den Berg J, Wlaschin JJ, Livak F, Callen E, Wong N, Lloyd EYH, Silberberg H, Sharma S, Chari R, Freeman T, Kim B, van Oudenaarden A, Chesler AT, Ward ME, Boxer LD, McHugh PJ, Chabes A, Le Pichon CE, Nussenzweig A
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Small-molecule inhibitors of the protein kinase DYRK as potential therapeutic candidates in cancer.
- Cell Chem Biol - published June 1, 2026
- Venkataramani P, Elkayam E, Garg A, Cheng KF, Altiti A, He M, Thakur K, Michalopoulou E, Gonzalez C, Felice C, Van Aelst L, Pappin D, Joshua-Tor L, Al-Abed Y, Tonks NK
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Staphylococcus aureus ZigA is implicated in survival in zinc-deplete and genotoxic environments.
- Microbiol Spectr - published June 1, 2026
- Enriquez KT, Weiss A, Perera YR, Bhatia I, Togashi M, Akizuki T, McDonald WH, Chazin WJ, Skaar EP
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Detangling knots: the intricate roles of G-quadruplexes in herpesvirus replication.
- J Virol - published June 1, 2026
- Lowery SA, Gordon SA, Paul A, Hill RS, Holehouse AS, Draganova EB
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The distinct trimeric structure of the immunodominant chlamydial antigen Major Outer Membrane Protein.
- Nat Commun - published June 1, 2026
- Guo Y, Shelby ML, D'haeseleer P, Pal S, Slepenkin A, Robinson BV, Otwinowski Z, Segelke BW, Coleman MA, Borek D, de la Maza LM
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Mechanism of lipid transfer by bridge-like protein VPS13A and the scramblase XK.
- Cell - published June 1, 2026
- Hu B, Álvarez D, Rocha-Roa C, Guyard V, Li D, Ahmed Y, Wang X, De Camilli P, Vanni S, Reinisch KM
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Host-Pathogen Interactions in Malaria: Invasion, Neutralization, and Evasion.
- Annu Rev Microbiol - published June 1, 2026
- Dickey TH, Tolia NH
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Erythroferrone antagonism of BMPs is governed by a composite heparin-binding motif.
- J Biol Chem - published June 1, 2026
- Mast EM, Hok L, Leach EAE, Thompson TB
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Atg23 interacts with both the N- and C-termini of Atg9 via a hydrophobic binding pocket.
- J Biol Chem - published June 1, 2026
- Bekkhozhin Z, Leary KA, Ragusa MJ
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Targeting the Energy-Coupling Factor Transporters: A Novel Antibiotic Drug Target in Streptococcus pneumoniae.
- J Med Chem - published June 1, 2026
- Diamanti E, Cremers AJH, Li Y, Exapicheidou I, Baumann C, Gibson P, Shams A, Martin L, Becker R, Setyawati I, Zeimetz L, Haupenthal J, Witschel M, Slotboom DJ, Herrmann J, Rox K, Hamed MM, Veening JW, Hirsch AKH
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A single-vesicle fluorescence microscopy platform to quantify phospholipid scrambling.
- Nat Struct Mol Biol - published June 1, 2026
- Veit S, Dearden GI, Menon KM, Noor F, Menon I, Morizumi T, Ernst OP, Menon AK, Pomorski TG
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Development of a recombinant single-cycle influenza viral vector as an intranasal vaccine against SARS-CoV-2.
- Sci Rep - published June 1, 2026
- Munro J, Melnyk D, Afzal M, Schimanski L, Cohen AA, Keeffe JR, Bjorkman PJ, James WS, Townsend AR, Tan TK
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Lipid trapping slows ball-and-chain inactivation in a calcium-activated potassium channel.
- Nat Commun - published June 1, 2026
- Sukomon N, Yoo HS, Williams-Noonan BJ, Fan C, Boiteux C, Perrino A, Scheuring S, Allen TW, Nimigean CM
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Mapping the monoclonal antibody landscape of human cytomegalovirus.
- J Virol - published June 1, 2026
- McClave MK, Heldwein EE
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Rapid Affinity Characterization of Cell-Free Expressed Nanobodies Directly in Lysate with Biolayer Interferometry via Antigen-Immobilized Biosensors.
- ACS Synth Biol - published June 1, 2026
- Lange B, Godin R, Schnicker NJ, Wadas TJ, Reuel NF
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Structural basis and immunogenic efficacy of porcine circovirus type 3 virus-like particle.
- Nat Commun - published June 1, 2026
- Su J, Tong X, Jiang Y, Li Y, Yan H, Liu Y, Wang Y, Su X, Sun Z, Wang M, Xia N, Bostina M, Li S, Pang W, Zheng Q, Tian K
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Structural evidence that a lipid plug controls K(2P)6.1(TWIK-2) function.
- Nat Commun - published June 1, 2026
- Mondal A, Niranjan S, Minor DL Jr
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Molecular basis of polyadenylated RNA fate determination in the nucleus.
- Nature - published June 1, 2026
- Bugai A, Hohmann U, Lorenzo A, Graf M, Fin L, Rouvière JO, Tirian L, Dou Y, Le Rest M, Polák P, Johnsen D, Jakobsen L, Andersen JS, Brennecke J, Plaschka C, Jensen TH
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Development of a Core Outcome Domain Set for Facial Aging.
- JAMA Dermatol - published June 1, 2026
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Saxiphilin is a broad-spectrum toxin sponge for C13-modified saxitoxins.
- Structure - published June 1, 2026
- Zakrzewska S, Chen Z, Park ER, Bhaskar RG, Bedell TA, Du Bois J, Minor DL Jr
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Dual CDK2 and CDK4/6 inhibition suppresses Rb/E2F signaling and enhances anti-leukemic activity in acute myeloid leukemia.
- Haematologica - published June 1, 2026
- Weisberg E, Chowdhury B, Garg S, Akatsu T, Ni W, Gokhale PC, Eschle BK, Grant S, Sattler M, DeCaprio JA, Nöltner L, Garcia J, Marinchev K, Galinsky I, Nath A, Stone RM, Griffin JD
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PARG Governs a PARylation-Ubiquitination Toggle that Stabilizes RAD51AP1 to Drive Homologous Recombination-Mediated Chemoresistance.
- Cancer Res - published June 1, 2026
- He H, Hu Y, Lu Y, Deng M, Bao Q, Zu D, Zhong Y, Zhang C, You C, Du X, Liu S, He Y, Liu M, Gao L, Gao X, Liu H, Huang Y, Chen Y, Rong D, Tainer JA, Jing J, Shi Y, Shen HM, Ye Z, Cheng X
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Targeting the METTL1/m7G axis as a therapeutic strategy in myeloid leukemia.
- Blood - published June 1, 2026
- Ren L, Zhang H, Bobileva O, Nai F, Bi H, Chan A, Baker GE, Dong L, Guarin D, Hu W, Li W, Leite I, Wang X, Zhang X, Xue M, Wang H, Qin H, Wu X, Ghoda L, Xu L, Zhang B, Li L, Wunderlich M, Mulloy JC, Jones CL, O'Leary SE, Li H, Rosen ST, Chen CD, Heisterkamp N, Perry JJP, Nam Y, Chen J, Caflisch A, Li X, Su R
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Correction: Exploitation of phage Carin-5's own DNA polymerase to sequence its T-hypermodified genome.
- Sci Rep - published June 1, 2026
- Sieskind R, Missoury S, Bonhomme F, Nogaret P, Lucas-Staat S, Monot M, Skurnik M, Baudoux AC, Delarue M
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Methicillin treatment reveals that FtsZ phosphorylation influences the cell division of Streptococcus pneumoniae.
- PNAS Nexus - published June 1, 2026
- Nagarajan SN, Manuse S, Juillot D, Claude L, Ravikumar V, Neumann E, Lavergne JP, Franz-Wachtel M, Macek B, Mijakovic I, Morlot C, Carballido-Lopez R, Grangeasse C
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Pooled combinatorial screening identifies transcription factor sets that drive hematopoietic progenitor-like cell fate.
- Cell Syst - published June 1, 2026
- Briggs JA, Cho J, Strebinger D, Joung J, Braun TW, Macrae RK, Li H, Zhang F
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A Bacillales-specific tubular scaffold essential for NADH dehydrogenase activity.
- Nat Commun - published June 1, 2026
- Seduk F, Osman R, Garcia PS, Bizien-Jaglin L, Juyoux P, Kosta A, Sauvage S, Maté MJ, Pierrel F, Lebrun R, Schoehn G, Yamaryo-Botté Y, Botté CY, Nicolet Y, Cherrier MV, Walburger A, Magalon A
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Metabolic cross-talk promotes persistence of Enterococcus in a model of polymicrobial catheter-associated urinary tract infection.
- Sci Adv - published June 1, 2026
- Zou Z, Pinkner JS, Obernuefemann CLP, Kleinschmidt KR, Sanick DA, Hickerson SM, Dodson KW, Henderson JP, Hultgren SJ, Caparon MG
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An implementation strategy bundle to improve home visit quality of the national child development program in Brazil: an implementation feasibility trial.
- Implement Sci Commun - published June 1, 2026
- Brentani A, Westgard CM, Chang-Lopez S, Silva Onofre AC, Peres NV, Bessa L, Raggio Colagrossi AL, Santos JL, Siqueira Cunha DF, Haidar J, Peterson HB, Walker S
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Mechanistic and antigenic boundaries of Henipavirus and Parahenipavirus glycoproteins.
- Nat Commun - published June 1, 2026
- May AJ, Lella M, Lindenberger J, Berkman A, Kumar U, Liu K, Dutta M, Barr M, Parks R, Lu X, Berry M, Powell A, Thompson AG, Sowdamini Nakka S, França CT, Huang X, Mrigwani A, Song K, Ilevbare V, Sammour S, Park CS, Devkota Adhikari R, Devkota P, Janowska K, Liu Y, Scapellato G, Spence TN, Mansouri K, Wiehe K, Sullivan NJ, Mason R, Edwards RJ, Saunders KO, Haynes BF, Acharya P
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Stable and Tunable Expression of Human Peripheral Myelin Protein 22 in Rat Schwann Cells.
- J Biol Chem - published June 1, 2026
- Wilkinson MC, Stefanski KM, Gowda PS, Carter BD, Sanders CR
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Conformational cycling of the Wntless transporter drives trafficking and secretion of Wnt morphogens.
- Nat Commun - published June 1, 2026
- Ge Y, de Almeida Magalhaes T, Wu H, van den Boomen DJH, Nguyen TU, Dou T, Yadav GP, Lee S, Wang Z, Lemoff A, Luo X, Menon SS, Zhang M, Wang J, Jin Z, Jiang J, Salic A, Huang P
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1,4-Dihydroxy-1,8-napthyridinone (DHN) analogs as HIV-1 reverse transcriptase-associated RNase H inhibitors.
- Bioorg Chem - published June 1, 2026
- Shahari MSB, Offei S, Zhang H, Prahlad J, Mahoney JP, Kirby KA, Sarafianos SG, Wang Z