News

User Tale: Resistance is Futile

Updated: Aug. 3, 2017

Celia Schiffer | University of Massachusetts Medical School Approximately 200 million people are infected with hepatitis C virus (HCV) worldwide. While novel drugs, such as protease inhibitors, are effective against the virus, resistance …

User Tale: Twist of Fate

Updated: June 29, 2017

Leemor Joshua-Tor got her first introduction to chemistry in 7th grade. The Weizmann Institute of Science had created an introductory chemistry class for the local middle school in Rehovot, Israel, where Joshua-Tor was …

Developer Tale: Pipeline Dreams

Updated: June 28, 2017

A year ago, Bridget Carragher and Clint Potter’s group broke the so-called three-angstrom barrier for electron microscopy (EM). Prior to their work, so many structures had been solved using EM at 3.4 or …

User Tale: Drug Designer

Updated: May 31, 2017

In his lab at the Rosalind Franklin University of Medicine and Science in North Chicago, John K. Buolamwini designs drugs. He’s currently focused on reformulating drugs called nucleoside analog drugs, which have been …

Software Tale: Unstructured

Updated: May 9, 2017

Sit down in front of a newly installed copy of CCP4 today, and you will find approximately 250 computer programs for solving protein structures. The list of programs includes several with catchy names, …

Developer Tale: Stop, Collaborate and Listen

Updated: May 9, 2017

Back in the mid-1970s, the British government funded several collaborative computing projects. Among them (14 in all) was Collaborative Computing Project 4, known by structural biologists as CCP4. "The idea was that computers …

Developer Tale: Mathematically Minded

Published: April 28, 2017

James Holton first got interested in structural biology in the late 1980s at a biochemistry summer camp as a high school sophomore. He was flipping through the textbooks and ran into the protein …

SBGrid Lunch Break with Tom Goddard

Updated: April 11, 2017

Tune in on April 11th to hear about the latest enhancements in Movie Making for cryoEM using ChimeraX. Tom Goddard, Programmer/Analyst at the UCSF Resource for Biocomputing, Visualization, and Informatics, will join us …

Developer Tale: Garbage Out

Updated: March 31, 2017

In 2011, Kay Diederichs welcomed longtime friend and colleague Andrew Karplus into his lab at the University of Konstanz in Germany. The two had met in the 1980s at the University of Freiburg …

SBGrid Workshop on EM Data Processing

Updated: March 30, 2017

SBGrid is pleased to host an Electron Microscopy Data Processing Workshop. This 1-day course will include an introduction to and hands-on tutorial for RELION 2.0 for single particle analysis. The workshop will be …

SBGrid Lunch Break with Frank Murphy

Updated: March 30, 2017

Join us on March 23rd to learn more about RAPD from Northeastern Collaborative Access Team (NE-CAT) Assistant Director Frank Murphy. RAPD is new software for automated MX data analysis. RAPD - New software …

SBGrid Lunch Break with Peter Eastman

Updated: March 2, 2017

Join us February 28th to hear a presentation from Peter Eastman on OpenMM, a tookit for molecular simulation. Dr. Eastman is Senior Software Engineer in Vijay Pande's lab at Stanford University. OpenMM Tuesday, …

Developer Tale: Wire Models, Wired

Updated: March 1, 2017

The molecular graphics software called Chimera, written and supported by a team of scientists in Tom Ferrin’s lab at the University of California, San Francisco (UCSF), has been cited over 7000 times and …

Developer Tale: Into Alignment

Updated: March 1, 2017

In 1987, when Geoff Barton was a graduate student learning computational structural biology at the University of London, just 6000 protein sequences were known, but their numbers were rising exponentially, and it was …

Software Tale: Computing Cellular Clockworks

Updated: March 1, 2017

Physicist Klaus Schulten once imagined becoming a dancer, relying on nothing but his own mind and body to perform. “But I was not a good dancer,” he says. “So my next thing was …

User Tale: Fixer Upper

Published: Feb. 27, 2017

Soon after starting his lab at Vanderbilt University in 2004, Brandt Eichman attended a DNA repair meeting in Bermuda. When the Keynote speaker mentioned two new glycosylases, enzymes that recognize and repair damaged …

SBGrid is now hosting PyMOLWiki

Updated: Feb. 23, 2017

We are happy to announce that effective Sept 12, 2016, the SBGrid Consortium began managing and maintaining PyMOLWiki. Many thanks to Jason Vertrees, who spent over 10 years creating, building, and maintaining this …

User Tale: Mobilizers

Published: Jan. 31, 2017

A few years ago, at a New Year’s Eve party in her neighborhood, Phoebe Rice mentioned, as you do, that she needed some methicillin-resistant Staphylococcus aureus (MRSA) strains. A neighbor responded: “Have you …

SBGrid Lunch Break: IOTA and PRIME

Updated: Jan. 30, 2017

Tune in January 17th, in a follow up to last week's webinar on cctbx.xfel and DIALS, to learn how to Get the most out of your XFEL data with IOTA and PRIME. Mona …

SBGrid Lunch Break with Aaron Brewster

Updated: Jan. 12, 2017

Please join us January 10th, in the first of two xfel webinars, to learn about Processing serial crystallographic data using cctbx.xfel and DIALS. Aaron Brewster, Project Scientist at Lawrence Berkeley National Labs, will …